NFL Week 4 Predictions: Lamar Jackson Rushing Score and Lions-Panthers Stat Projections

Lamar Jackson is projected to record a rushing touchdown against the Titans while Jameson Williams is predicted to catch seven passes for 114 yards.

Week 4 of the 2026 NFL season opened with the Cleveland Browns defeating the Pittsburgh Steelers 27-24 on Thursday night. Heading into the remaining 15 games, ESPN analyst Matt Bowen predicts Baltimore Ravens quarterback Lamar Jackson will record a rushing touchdown on a designed carry against the Tennessee Titans. Jackson enters the matchup averaging 5.7 carries per game with four passing touchdowns and one rushing score on the season.

Analytics writer Seth Walder projects Detroit Lions wide receiver Jameson Williams will finish with seven receptions, 114 yards, and one touchdown against the Carolina Panthers. Williams currently averages 1.2 yards per route run. The Panthers defense will be without cornerbacks Jaycee Horn and Mike Jackson due to injuries. Additionally, Walder expects Rams cornerback Trent McDuffie to record an interception and allow only seven receiving yards against an Eagles team playing without DeVonta Smith.

In betting projections, Pamela Maldonado identifies the Denver Broncos as +3 underdogs capable of upsetting the San Francisco 49ers, who will be without edge rusher Nick Bosa. The Atlanta Falcons are also picked to win outright against the New Orleans Saints, as the Saints will miss running back Travis Etienne Jr. and left tackle Kelvin Banks Jr. The Dallas Cowboys, led by Dak Prescott and CeeDee Lamb, are projected to upset the Houston Texans.

Fantasy sleepers for the weekend include Miami Dolphins receiver Malik Washington, who saw 10 targets last week, and Carolina Panthers tight end Darren Waller. Commanders quarterback Marcus Mariota is also highlighted as a sleeper against a Colts defense allowing the fifth-most fantasy points to his position. Mariota recently threw three touchdown passes against the Seahawks.